TRANSLATING BASIC RESEARCH IN CANCER PATIENT CARE

Translating basic research in cancer patient care

With the Wooden Kit advent of molecular targeted therapies and the development of high-throughput biotechnologies, it has become evident that progress in cancer research is largely due to the creation of multidisciplinary teams able to plan clinical trials supported by appropriate molecular hypotheses.These efforts have culminated in the identifica

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Synthetic seismicity for the San Andreas fault

Because historical catalogs generally span only a few repetition intervals of major earthquakes, they do not provide much constraint on how regularly earthquakes recur.In Tool Set order to obtain better recurrence statistics and long-term probability estimates for events M ? 6 on the San Andreas fault, we apply a seismicity model to this fault.The

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E2F1-mediated upregulation of p19INK4d determines its periodic expression during cell cycle and regulates cellular proliferation.

BACKGROUND: A central aspect of development and disease is the control of cell proliferation through regulation of the mitotic cycle.Cell cycle progression and directionality requires an appropriate balance of positive and negative regulators whose expression Scales must fluctuate in a coordinated manner.p19INK4d, a member of the INK4 family of CDK

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